Modern approaches to the treatment of peptic ulcer disease and prospects for the use of biological therapy

Digestive diseases are the sixth leading cause of death in world and accounted for more than 2.5 million deaths 2019. In Ukraine, mortality from digestive system is recorded as one highest world, place general structure occupied by peptic ulcer disease (РUD).
 The aim study. Summarize current information on etiology pathogenesis РUD characterize modern approaches to treatment patients with prospects biological therapy.
 Materials methods. Publications were selected based PubMed, Clinical Key Elsevier, Cochrane Library, eBook Business Collection, Google Scholar databases, which covered etiology, pathogenesis, РUD.
 Results. Standard first-line anti-Helicobacter therapy consists a proton pump inhibitor two antibiotics, such clarithromycin amoxicillin or metronidazole. A promising direction use therapy. According literature sources, prophylactic cryoextract placenta indomethacin gastric lesions has an anti-ulcer effect at level 69.1 % 92.1 diclofenac sodium lesions. addition, specified capable leveling gastrotoxic acetylsalicylic acid, ibuprofen, stress factor chemical ulcerogens.
 Conclusions. Today, there great need cell that could be put into practice clinically relevant volumes. most directions gastroenterology considered mesenchymal stem cells agents obtained fetoplacental complex.